What is the papulopustular reaction of the eyelids and brow, and what causes it?
In recent years, numerous pharmaceuticals have been produced that can block certain cell receptors. The most widely used, currently marketed targeted therapy pharmaceuticals are: The most widely used, currently marketed targeted therapy pharmaceuticals are: Cetuximab (Erbitux), Panitumumab (Vectibix), Gefitinib (Iressa), Erlotinib (Tarceva), Trastuzumab (Herceptin), Lapatinib (Tyverb).
Papulo-pustular reaction is the most frequent event during treatment with EGFR inhibitors. It is manifested by the appearance of inflammatory papules or pustules at the level of hair follicles. This occurs especially in areas rich in sebaceous glands such as the face and upper torso. This papulopustular reaction also commonly appears on the eyelids and the brow. Here, it causes specific, cosmetic issues such as eyelash and eyebrow drooping. Pus from ruptured pustules can also adhere to the eyelashes.
How to treat papulopustular reactions on the eyelids and brow
To counteract this annoying side effect, the recommended cosmetic treatment is to apply PEG Balm every evening. This ointment works by absorbing moisture and helps soften the skin. The ointment is applied on the outside with the eyes closed. Alcohol-free disinfectant solutions are recommended for cleaning the eyelid.
