What is skin rash as an effect of biological therapy?

In recent years, numerous pharmaceuticals have been produced that can block certain cell receptors. The most widely used, currently marketed targeted therapy pharmaceuticals are: Cetuximab (Erbitux), Panitumumab (Vectibix), Gefitinib (Iressa), Erlotinib (Tarceva), Trastuzumab (Herceptin), Lapatinib (Tyverb). While producing positive results in cancer treatment, these pharmaceuticals can cause unwanted side effects including skin reactions. A common reaction to targeted therapy is the appearance of inflammatory papules or pustules at hair follicles, especially in areas rich in sebaceous glands such as on the face and upper trunk. Papulopustular outbreaks or follicular rashes in response to treatment are ranked into four grades according to their intensity, which can vary. At the highest grade, the reactions can be very serious, causing plaques, crustiness, pain, and burning.

How to treat skin reactions to targeted therapy

  • Treatment for grades one and two: Reactions at this level usually do not require specific treatment. Instead, avoid any additional irritation by using potassium permanganate solution to wash the skin. After drying, apply Lenitive Cream.
  • Treatment for grades three and four: Apply a small amount of 2S Cream to the affected area each evening and massage until completely absorbed.

Use the natural, breathable opaque Clay Color as make up. It is free from water, emulsifiers, preservatives, dyes and fragrances.
Use the gentle, non-foaming Eudermic Cleansing Base as both a make-up remover and cleanser.

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